Leaders

Glioblastoma awareness day

Published

3 years ago

July 22, 2021

ticker NEWS

Kazia Therapeutics Limited (ASX: KZA; NASDAQ: KZIA) is an oncology-focused drug development company.

Their lead program is paxalisib, which is being developed to treat glioblastoma (GBM), the most common and aggressive form of primary brain cancer in adults. There are few treatment options for sufferers of GBM and around 65% of sufferers do not respond to currently available treatments. The condition affects around 133,000 people globally per annum and the potential addressable market is worth more than US$1 billion.

Kazia’s drug paxalisib, commenced recruitment to GBM AGILE, a pivotal study in glioblastoma, in January 2021. Eight additional studies are active in various forms of brain cancer. Paxalisib was granted Orphan Drug Designation for glioblastoma by the US FDA in February 2018, and Fast Track Designation for glioblastoma by the US FDA in August 2020. Kazia is also developing EVT801, a small-molecule inhibitor of VEGFR3, which was licensed from Evotec SE in April 2021. Preclinical data for EVT801 has shown it to be active against a broad range of tumour types and has provided compelling evidence of synergy with immuno- oncology agents.

A phase I study is expected to begin in CY2021. Competitive Advantages: – Lead program, paxalisib, sourced from the world’s most successful cancer drug developer, Genentech – Experienced team with extensive backgrounds in big pharma and biotech – Around 65% of GBM sufferers do not respond to current treatments – Multiple shots on goal with collaborations progressing in other cancers; largely funded by participating hospitals.

For more information, head to their website.

Leaders

Niche accountants proving essential to e-commerce success

Published

4 hours ago

October 9, 2024

ticker NEWS

Expert explores the key benefits of partnering with accountants who specialise in niche industries.

In today’s fast-paced digital world, having an accountant who understands the intricacies of e-commerce can make all the difference in your business’s success.

Specialist accountants understand the specific needs of e-commerce businesses, helping to maximise tax savings, streamline operations, and improve financial health.

Niche accountants can identify opportunities to scale, optimise profit margins, and implement strategies that align with your business goals, ultimately drive growth.

Chris Rivera, Founder of The Ecommerce Accountants, joins to share his key insights into the industry.

#featured

Leaders

Israeli claims airstrikes have killed two successors to Hezbollah’s slain leader

Published

9 hours ago

October 9, 2024

ticker NEWS

The update comes as Israel expands its ground offensive against the Iran-backed group with a fourth army division deployed into south Lebanon.

Israel Prime Minister Benjamin Netanyahu spoke in a video released by his office hours after the deputy leader of Hezbollah left the door open to a negotiated ceasefire, reports Reuters

Israel’s military said on Tuesday that heavy air strikes against underground Hezbollah installations in southern Lebanon over the prior 24 hours killed at least 50 fighters including six sector commanders and regional officials. #featured #trending

Leaders

Reports show that workplace mental health is at an all-time crisis point, demanding proactive strategies

Published

1 day ago

October 8, 2024

ticker NEWS

As Mental Health Week highlights the urgency of action, businesses are being urged to shift their mindset from compliance to proactive mental health strategies.

As Mental Health Week highlights the urgency of action, businesses are looking to implement crucial forward actions to boost workplace resilience.

Mental Health Crisis: Workplace mental health and wellbeing are at a crisis point, demanding urgent action from businesses.
Costly Impact: Business owners and senior leaders recognise the financial strain mental health issues place on organisations, yet solutions remain unclear.
Leveraging Laws: Psychological safety laws offer a framework to reverse the costly impact of workplace mental health challenges.
Mindset Shift: A change in approach is required, viewing mental health regulations as opportunities for long-term, sustainable success rather than a compliance burden.

Sharné Lategan, Psychological Safety Expert and Growth Mindset Coach of Grow and Expand, joins to share her expert analysis into workplace physiology, bringing awareness during Mental Health Week.