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Glioblastoma awareness day

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Kazia Therapeutics Limited (ASX: KZA; NASDAQ: KZIA) is an oncology-focused drug development company.

Their lead program is paxalisib, which is being developed to treat glioblastoma (GBM), the most common and aggressive form of primary brain cancer in adults. There are few treatment options for sufferers of GBM and around 65% of sufferers do not respond to currently available treatments. The condition affects around 133,000 people globally per annum and the potential addressable market is worth more than US$1 billion.

Kazia’s drug paxalisib, commenced recruitment to GBM AGILE, a pivotal study in glioblastoma, in January 2021. Eight additional studies are active in various forms of brain cancer. Paxalisib was granted Orphan Drug Designation for glioblastoma by the US FDA in February 2018, and Fast Track Designation for glioblastoma by the US FDA in August 2020. Kazia is also developing EVT801, a small-molecule inhibitor of VEGFR3, which was licensed from Evotec SE in April 2021. Preclinical data for EVT801 has shown it to be active against a broad range of tumour types and has provided compelling evidence of synergy with immuno- oncology agents.

A phase I study is expected to begin in CY2021. Competitive Advantages: – Lead program, paxalisib, sourced from the world’s most successful cancer drug developer, Genentech – Experienced team with extensive backgrounds in big pharma and biotech – Around 65% of GBM sufferers do not respond to current treatments – Multiple shots on goal with collaborations progressing in other cancers; largely funded by participating hospitals.

For more information, head to their website.

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Improving digital experience is everything

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All eyes are now on businesses as they navigate the online world.

Organisations are trying to optimise their website, social media and mobile applications to capture customers, and provide a flawless digital experience.

But, how can this be done?

“There is a real thirst for leveraging the data of customer behaviour,” Optimizely‘s Paul North revealed to Ticker News. “This is all a part of the customer digital experience online.”

North also spoke about the importance of the company’s ‘data core service’ – a free service for clients, to better understand customers and how it can help businesses to grow.

“We are getting queries from our customers, about what their customers are doing online,” he adds. “every touchpoint you ave with a customer is a chance to get to know them better.

“You also get the chance to understand them, the content they are interested in, and to enrich their experience.”

North also went on to detail why a personalised aspect is crucial in a fast-paced world.

“Everyone in the digital space talks about the three-second flicker,” he continues. “If you don’t have the engagement in real-time, you lose them to another digital property.

“This could be your competitor, or another service, or another avenue of interest that the end user may have.

“Our aim is to help organisations contextualise customer experiences in real-time using Artificial Intelligence and a data bank built up, and by doing this, the experience become relevant and contextualised, keeping people engaged with your brand.”

For more information, head to their website.

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Training to your peak with Maximum Potential Calisthenics

The way people train and take care of their body has significantly changed over the years, with bodyweight calisthenics becoming a popular choice for many.

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The way people train and take care of their body has significantly changed over the years, with bodyweight calisthenics becoming a popular choice for many.

Maximum Potential Calisthenics‘ Nathan Leith says there has been a boom over the past 12-24 months in the industry.

“There has been a decrease over the past decade of people wanting to go to the gym,” Leith points out on Ticker News. “They don’t want to build that huge, massive physique.

“A structural shift towards functional training has been seen.

“People want to stay mobile, build strength and learn a few more skills.”

Leith argues there are benefits for people to get into Calisthenics, as it appeals to anyone.

“There is no need for weights, or a gym,” he highlights. “It can be done outside and people seem to love it.”

“Anybody is able to do it, especially if people are able to do the moves and then improve on it.”

Leith also points out form and safety are paramount when doing the exercises, which is why they keep their class sizes small.

“People want to get their form and detail correct,” Leith adds. “Before anyone signs up, we will assess how people perform certain actions. and history.”

For more information, head to their website.

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HCL hitting cricket for six!

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HCL Technologies is a next-generation global technology company that helps enterprises reimagine their businesses for the digital age.

Their technology products, services, and engineering are built on four decades of innovation, with a world-renowned management philosophy, a strong culture of invention and risk-taking, and a relentless focus on customer relationships.

HCL offer an integrated portfolio of products, solutions, services, and IP through our Mode 1-2-3 strategy, built around Digital, IoT, Cloud, Automation, Cybersecurity, Analytics, Infrastructure Management, and Engineering Services, amongst others.

With a worldwide network of R&D, innovation labs and delivery centres, and 187,634 ‘Ideapreneurs’ working in 50 countries, HCL serves leading enterprises across key industries, including 250 of the Fortune 500 and 650 of the Global 2000.

For more information, head to their website.

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