Leaders

Glioblastoma awareness day

Published

3 years ago

July 22, 2021

ticker NEWS

Kazia Therapeutics Limited (ASX: KZA; NASDAQ: KZIA) is an oncology-focused drug development company.

Their lead program is paxalisib, which is being developed to treat glioblastoma (GBM), the most common and aggressive form of primary brain cancer in adults. There are few treatment options for sufferers of GBM and around 65% of sufferers do not respond to currently available treatments. The condition affects around 133,000 people globally per annum and the potential addressable market is worth more than US$1 billion.

Kazia’s drug paxalisib, commenced recruitment to GBM AGILE, a pivotal study in glioblastoma, in January 2021. Eight additional studies are active in various forms of brain cancer. Paxalisib was granted Orphan Drug Designation for glioblastoma by the US FDA in February 2018, and Fast Track Designation for glioblastoma by the US FDA in August 2020. Kazia is also developing EVT801, a small-molecule inhibitor of VEGFR3, which was licensed from Evotec SE in April 2021. Preclinical data for EVT801 has shown it to be active against a broad range of tumour types and has provided compelling evidence of synergy with immuno- oncology agents.

A phase I study is expected to begin in CY2021. Competitive Advantages: – Lead program, paxalisib, sourced from the world’s most successful cancer drug developer, Genentech – Experienced team with extensive backgrounds in big pharma and biotech – Around 65% of GBM sufferers do not respond to current treatments – Multiple shots on goal with collaborations progressing in other cancers; largely funded by participating hospitals.

For more information, head to their website.

Leaders

Expert explains how AI is transforming advertising with precision targeting

Published

1 week ago

January 9, 2025

ticker NEWS

AI and data is revolutionising ads, helping fill every last seat in the metaphorical plane.

Traditional targeting methods often relied on invasive data collection and manual processes, such as gathering demographic information from surveys or databases. AI, however, analyses anonymous user behaviour—such as browsing habits and content engagement—on a granular level to create highly precise user segments.

AI also excels in real-time ad optimisation, interpreting thousands of data signals to enhance campaign performance. Advertisers can now target audiences with 10 times the precision, ensuring users see ads tailored to their interests.

Using an aeroplane metaphor, Rajiv Khaneja, CEO and founder of AdButler, likened ineffective ad targeting to flying a half-empty plane—costly and inefficient. AI, on the other hand, helps fills the plane with people interested in the businesses offer, ensuring advertisers maximise the value of their spend.

Rajiv emphasised that as the advertising industry evolves, adopting AI-driven solutions is no longer optional. Businesses failing to embrace these tools risk falling behind as advertisers prioritise platforms that offer better audience alignment and measurable results.

Leaders

Microsoft to invest $80 billion in AI data centers

Microsoft to invest $80 billion in AI-enabled data centers by fiscal 2025, according to CNBC report.

Published

2 weeks ago

January 6, 2025

ticker NEWS

Microsoft to invest $80 billion in AI-enabled data centers by fiscal 2025, according to CNBC report.

In a recent report by CNBC, Microsoft announced plans to invest $80 billion in artificial intelligence-enabled data centres during fiscal year 2025.

This significant expenditure is aimed at enhancing the company’s capabilities in AI and data processing.

As part of its strategy, Microsoft aims to increase its competitive edge in the rapidly growing AI sector. The funding will support the development of infrastructure necessary for AI applications and services.

This move also signals Microsoft’s confidence in the potential growth of AI-enabled solutions in the coming years. The investment decision has potential implications for job creation and economic activity in regions hosting new data centres.

Leaders

Unlocking energy savings in the evolving HVAC landscape

Published

1 month ago

December 19, 2024

ticker NEWS

Tips, trends, and the future of sustainable home comfort.

Julian Picard, Owner & CEO of Centerline Mechanical LLC, shares insights on optimising HVAC systems to save energy, the shift toward heat pumps, rising installation costs, and the need to engage younger generations in the trades.

Homeowners are reaping the benefits of modern HVAC systems that optimise energy use with advanced inverters. Unlike older, single-stage models that operate at full capacity, today’s systems adjust their output based on a home’s actual needs.

This innovation reduces energy consumption significantly, especially in homes that have undergone insulation upgrades.Government rebates, like the $16,000 available in Massachusetts, further incentivise adoption.

Simultaneously, younger generations are increasingly drawn to this sustainability trades, with Gen Z technicians leveraging digital expertise to innovate and thrive in hands-on roles.

This growing interest ensures a robust future for the HVAC and energy sectors.