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Five things we’ve learned about long COVID

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We got some key things wrong about long COVID. Here are 5 things we’ve learnt

In late 2020 as we hid from COVID behind the moat of “fortress Australia”, we started to hear that in some people, COVID symptoms persisted for months. They were called “long haulers” or had “long COVID”.

Contrary to what we’d expected, it wasn’t just affecting people’s lungs or breathing. Long haulers were experiencing an enormous range of other symptoms: fatigue that was worse after activity, muscle aches and pains, headache, and cognitive dysfunction or brain fog.

A parliamentary inquiry is currently investigating Australia’s response to long COVID – patient experiences, the health system’s response and what the latest research shows.

Three years in

It’s now clear we got some key things wrong about long COVID earlier in the pandemic. Three years in, and with an estimated 65 million people affected by long COVID, here are five things we now know or suspect about the condition.

We now know full recovery of lung function is not guaranteed for people with long COVID: one in five still complain of severe breathlessness and 10% have severe functional impairment.

Among people admitted to hospital, studies report impaired lung function, abnormal chest scans, impaired capacity to exercise and persistent breathlessness months after leaving hospital, especially for those who needed breathing support in ICU.

In those people who where hospitalised with COVID-19 pneumonia and who have persistent breathlessness, pulmonary (lung) rehabilitation improves quality of life and exercise tolerance. While this evidence is not strong, it is consistent, across one randomised control trial and seven observational studies.

We need a national approach to assess all patients who survive hospitalisation, to determine if they are still breathless and ensuring they have access to pulmonary rehabilitation.

Early on, we failed to understand COVID would increase the risk and worsen other chronic diseases.

Since then, large population studies have clearly documented people with long COVID are at increased risk of stroke and heart disease and an increased risk of diabetes.

Time to recover

These problems are more likely in those who are socially disadvantaged, and unable to have sufficient time to recover.

We initially thought of long COVID as a single disorder. We now know it’s a complex condition, caused by a number of different factors. Emerging evidence suggests this includes:

impaired immunity

the development of autoantibodies (where the immune system attacks the self)

the persistence of the SARS-CoV-2 virus

microclots (small blood clots and/or damage to blood vessels).

Studies investigating these causes are still small and observational – and these factors are likely overlap and vary among sufferers. The only way to address these issues will be with further research.

A number of treatments are advocated, but they all need to be tested in properly controlled trials, too few of which are in progress.

In the past we had not devoted sufficient resources to treat post-infectious or immune syndromes such as myalgic encephalitis or chronic fatigue syndrome (ME/CFS). These syndromes are defined by excessive fatigue, which worsens after exertion, and include cognitive impairment or brain fog.

Disease and disability

These symptoms are responsible for much of the disease and disability associated with long COVID in many people and are often more prevalent than respiratory problems.

Severe cases of long COVID, ME/CFS and other post-infectious syndromes may include a condition known as POTS (postural orthostatic tachycardia syndrome), where an excessive heart rate results in falls in blood pressure with even mild exertion.

Unlike survivors of COVID pneumonia, people with POTS are much less likely to benefit from traditional exercise-based rehabilitation programmes. Such programs may even exacerbate their symptoms.

Instead, approaches are proposed that have been previously applied to ME/CFS and POTS are proposed, including exercise pacing, and medication regimes. However, there is a lack of good evidence, and while trials are underway, they are few, especially in Australia.

Finally, there has been the problem of attributing long COVID to poor mental health. While worsened mental health often accompanies chronic disease, this link for long COVID has been overstated and we are at risk of dismissing the physiological problem.

A large population study of more than 1.3 million people following COVID demonstrated that while there was an initial increase in anxiety and depression, it was transient, unlike features of long COVID such cognitive dysfunction.

COVID treatment has focused on the acute life-threatening illness and largely ignored the long-term consequences. But long COVID isn’t a problem that will disappear. It requires investigation into the illness it causes, robust clinical trials into treatments and effective models of care. This is not currently happening.

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Cyber security shifts redefine critical infrastructure in APAC

Cyber security evolution prompts redefinition of critical infrastructure in Asia Pacific amid rising digital threats

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Cyber security evolution prompts redefinition of critical infrastructure in Asia Pacific amid rising digital threats.

In Short:
– Cyber security incidents in Asia Pacific redefine critical infrastructure, expanding its scope beyond just industrial machinery.
– New strategies emphasise visibility to protect crucial sectors like banking, finance, and telecommunications from cyber threats.

The rise in cyber security incidents in Asia Pacific is reshaping the definition and protection of critical infrastructure. New digital and operational technology risks are prompting stakeholders to reconsider conventional beliefs that critical infrastructure is primarily industrial machinery behind high fences.

Michael Fisher from Garland Technology discusses this evolving landscape. Critical infrastructure now encompasses essential services such as banking, finance, and telecommunications, expanding beyond traditional definitions.

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The convergence of IT and operational technology (OT) networks increases cyber security risks. Many OT services were not designed with cyber security in mind, leaving them vulnerable to cyber attacks. Industries most at risk include telecommunications, banking, finance, and utilities, where any disruption can significantly impact society.

Increased Visibility

Fisher highlights that traditional cyber security alone is insufficient to secure these infrastructures. Effective protection requires a new approach focused on visibility. Garland Technology’s mission is to provide visibility to upstream cyber security platforms, eliminating blind spots.

Governments and businesses must recognise their roles in combatting cyber threats. Australia’s Security of Critical Infrastructure Act is a step towards increasing corporate responsibility in recognising critical infrastructure and ensuring compliance with security measures.


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Electric vehicles transform last mile delivery market

Australia’s last-mile delivery is rapidly adopting electric vehicles, fueled by green initiatives and insights from expert Joe Sofra.

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Australia’s last-mile delivery is rapidly adopting electric vehicles, fueled by green initiatives and insights from expert Joe Sofra.


The shift towards electric vehicles (EVs) for last mile delivery is accelerating globally, with Australia expected to see significant growth.

Companies and retailers are increasingly adopting greener solutions, driven by supporting government initiatives.

Joe Sofra from ANC discussed the current state of the last mile EV market.

#ElectricVehicles #Sustainability #LastMileDelivery #Innovation #Australia


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Trump gives Hamas ultimatum for Gaza peace plan acceptance

Trump gives Hamas deadline to accept Gaza peace plan amid rising pressure from Arab states and ongoing conflict in the region

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Trump gives Hamas deadline to accept Gaza peace plan amid rising pressure from Arab states and ongoing conflict in the region

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In Short:
– Trump gives Hamas three to four days to accept a U.S.-backed Gaza peace plan, warning of consequences.
– Hamas calls the plan biased and insists on a complete Israeli withdrawal before considering any agreement.
U.S. President Donald Trump has given Hamas three to four days to accept a U.S.-backed peace plan for Gaza, warning of severe consequences if they reject it.The plan, shared by mediators Qatar and Egypt, emerged after Israeli Prime Minister Benjamin Netanyahu endorsed it during a visit to the White House. Hamas, which was not part of the talks, is expected to review the proposal that calls for disarmament, a previously rejected demand.

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Trump stated that support for the plan came from both Israeli and Arab leaders, and he emphasised the need for Hamas to respond promptly. The proposal includes a ceasefire, hostage exchanges, an Israeli withdrawal from Gaza, and disarmament of Hamas, along with a transitional government.

A Hamas source described the plan as biased towards Israel and containing unacceptable conditions.

The group maintains that a complete Israeli withdrawal is a prerequisite for their agreement to any deal, while they are unwilling to disarm.

Pressure Mounts

Hamas faces significant pressure as foreign ministers from Saudi Arabia, Jordan, the UAE, Qatar, and Egypt have supported the initiative. Turkey’s intelligence head is also set to join discussions in Doha, marking a new level of mediation.

Despite expressing initial support, Netanyahu is cautious about the plan’s implications for Palestinian statehood and faces pressure from his coalition. Public sentiment in Gaza reflects a desire for peace, albeit with scepticism about the sincerity of both Trump and Netanyahu’s commitments.


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