Syrian rebels ousted Bashar Assad after a 13-year civil war, prompting a shift in the region’s dynamics that presents risks and opportunities for the US.

President Biden acknowledged Assad’s removal as a historic opportunity, signaling the need for careful US engagement to avoid chaos in Syria.

Experts highlight this change as a chance to weaken Iran’s regional influence, as the overthrow of Assad hinders Iran’s strategic interests.

The US has had limited involvement in Syria, focusing mainly on combating ISIS, which complicates its response to the new power vacuum.

Did Iraq become a flourishing democracy post-Saddam. How about Afghanistan post-Taliban. How about Libya post-Gaddafi. I’m sure Syria post-Assad will be a successful regime change operation.

20 straight years of this stuff and people still don’t get it.

— Clint Russell (@LibertyLockPod) December 7, 2024

Expectations suggest a low-level US campaign against ISIS will continue until a stable government is established, with efforts to maintain order and support allies.

The end of Assad’s rule has opened a security vacuum that extremist groups may exploit, further jeopardizing the humanitarian situation.

Iran and Russia also seek to reassert their influence following Assad’s departure, which could lead to competition for power among various factions.

Key figures, including the leader of Hayat Tahrir Al-Sham, Abu Mohammad al-Jolani, may vie for control in the power vacuum, raising concerns given the group’s past affiliations with terrorism.

Washington faces the challenge of engaging with groups like HTS while avoiding further destabilization.